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Diabetes & Obesity

Product name

Adiponectin high sensitive ELISA (TECO®)

Total Human Adiponectin
Cat-Nr. TE1013
Range 1 – 100 ng/ml native Adiponectin
Sensitivity < 0.6 ng/ml
Incubation time 2 hours
Sample volume 5 µl (dilute >1:300 serum and plasma). For other biological fluids see protocol.
Sample type

Serum, heparin plasma, breast milk, urine, saliva, CSF, cell culture
Sample preparation

Blood collection - fasting is recommended.
Samples are stable for maximum 2 days at room temperature. Long-term storage stable for maximum 2 years at -20 °C.
Max. 5 freeze and thaw cycles.
Reference values
  mg/l
Men Adult 8-10
Female Adult 10-12
cut-off 10


Comprehensive clinical reference data related to age and gender are available for this test.
Species

Human
Tests 96
Method ELISA
Intended use

Adiponectin is a 30kDa protein and its percentage in serum proteins is 0.01%. In vivo, it appears with different oligomers and it is mainly synthesized by adipocytes. Until now, IGF-1 is the only known natural inductor of synthesis.
Low Adiponectin levels are closely associated with insulin resistence and metabolic syndrome as well as an increased risk of type 2 diabetes mellitus and cardiovascular disease.
Today, Adiponectin is thought to act as an endogenic insulin sensitizer by decreasing excessive glucose levels without increasing insulin concentrations and by stimulating the burning of adipose tissue in muscle and liver.
Adiponectin is associated with glucose and lipid metabolism and is assumed to have direct antiatherogenic characteristics. Furthermore, it is involved in inflammatory processes.

Clinical significance:
• Obesity
• Atherosclerosis
• Energy metabolism
• Coronary artery disease
• Metabolic syndrome
• Polycystic ovary syndrome (PCOS)
  Product informations