Diabetes & Obesity
| Product name |
Resistin |
| Cat-Nr. | E50 |
| Range | 20 – 1000 pg/ml |
| Sensitivity | 12 pg/ml |
| Incubation time | 4 hours |
| Sample volume | 15 µl (dilute 1:21; recommended) |
| Sample type |
Serum, plasma, cell culture medium, salvia, breast milk and urine. |
| Sample preparation |
Haemolytic samples appear to show falsely high Resistin levels. Whole blood should be chilled as soon as possible following collection. Serum and plasma samples are stable for maximal 2 days at room temperature. Long-term storage at -20°C, stable for maximal 2 years. Maximum 3 freeze/thaw cycles. |
| Reference values |
Women: 7.0 ng/ml +/- 2.5 SD (referred to BMI ~ 25 kg/m²) |
| Species |
Human |
| Tests | 96 Tests |
| Method | ELISA |
| Intended use |
Resistin (FIZZ3) is a hormone influencing fat metabolism and inflammation processes. In humans, it is expressed in bone marrow and transported by macrophages into adipose tissue. Resistin stimulates pre-adipocyte proliferation and lipolysis of mature adipocytes probably by influencing MAPK signaling. With regard to the importance of Resistin in disorders of energy metabolism, a significant reduction could be shown in patients with anorexia nervosa. It has been demonstrated that Resistin enhances the expression of specific cell markers such as VACM-1 and ICAM-1 and thus may influence endothelial inflammatory processes, and thereby arteriosclerosis. Moreover, due to its association with Endothelin-1, Resistin also plays a role in cardiovascular diseases. Resistin is relevant to medical conditions such as: |
| Product informations |
